In the recent years, the importance of Herbal drugs in Medicine has tremendously increased because of their fewer side effects.Pracetamol is an Antipyretic drug commonly used for treatment of fever. Over dose of Paracetamol induces Hepatotoxicity by metabolic activation; therefore it selectively causes toxicity in liver cells maintaining semi-normal metabolic function. This book reveals the Hepatoproctective activity of cassia obtusifolia seeds against paracetamol induced Hepatotoxicity.
This book provides a systematic and comprehensive coverage of the Phytochemical and Pharmacological Antidiabetic Screening of Cassia Tora Linn. In the field of Pharmacy (Pharmaceutical Chemistry, Pharmacology, Pharmacognosy). This book cover introduction, plant profile, literature review, material and methods, result, conclusion, future scope of Phytochemical and Pharmacological Antidiabetic Screening of Cassia Tora Linn.
Over the past few years, there is a growing trend all over the globe to shift from synthetic to natural products. It is high time now to consider neglected and little known botanicals to cure diseases, which create challenging problems in agriculture and pose real economic and environmental threats. Plant diseases are the major biotic constraints to crop growth and causes variety of damage and significant yield loss. New approaches involving botanical fungicides are considered as alternative to synthetic fungicides as they maintain low mammalian toxicity and biodegradability. Species of genus Cassia have been of special interest due to their good therapeutic value. This book deals with the evaluation the antifungal activity of Cassia spp.against major phytopathogenic fungi, followed by identification and characterization of its active ingredient(s).This study suggests, Cassia laevigata has potent antifungal activity,which may be used as a new cost effective botanical fungicide. This book, therefore,useful to professionals in agriculture, plant pathology and plant biochemistry.
Chickpea (Cicer aretinum L.) is the third important pulse crop in the world. It is a rich source of vegetable protein for human nutrition. Ascochyta blight caused by fungus Ascochyta rabiei is the major disease limiting chickpea productivity worldwide. It causes high yield loss in chickpea annually and may cause total crop failure under epidemic conditions. Management strategies are aimed at preventing the occurrence of disease and limiting its spread. Use of fungicides to control this disease is effective, but pesticides pollute the environment and cause health hazards. Botanical derivatives are more environmentally safe than synthetic chemicals. Cassia fistula is well known for its pharmaceutical, antifungal & antimicrobial properties. So, in present study the antifungal activity of C. fistula was evaluated against the chick pea blight.
Cassia fistula Linn. (Purging cassia, Golden shower, Amaltas) is widely grown as an ornamental plant and well known traditional plant in India. The plant is having antioxidant activity, anti-inflammatory, laxative, wound healing, hepato-protective, antitussive, cardiovascular activity, antiulcer, antibacterial agent, larvicidal, ovicidal and antifertility effect. The aim was to search for anti-hypothyroidism activity of aqueous and ethanolic extract of Cassia fistula leaves. Aqueous and ethanolic extract of Cassia fistula leaves were investigated for its potential to protect hypothyroidism against hypothyroidism induced by propylthiouracil (PTU) in rats. fT3, fT4, TSH, cholesterol level and changes in body weight were used for evaluation of antihypothyroidism activity. Treatment with both extracts of Cassia fistula in dose of 300 mg/kg significantly increased fT3, fT4 and decreased TSH and cholesterol level compared with control group (p>0.001).Based on the studies we concluded that the ethanolic and aqueous extracts of Cassia fistula leaves might contain some active principles against hypothyroidism.