Book DescriptionInnovation in the Pharmaceutical Industry traces the discovery and development of drugs in Japan and the UK both historically and sociologically. It includes sixteen case studies of major pharmaceutical developments in the twentieth century, encompassing, among others, beta-blockers, beta-stimulants, inhaled steroids and histamine H2-antagonists. The book illustrates that the four stages of drug development - namely compound, application, organizational authorization and market - are interactively shaped by heterogeneous actors and institutions. The book also identifies three different types of pharmaceutical development - paradigmatic innovation, application innovation and modification-based innovation, all with distinguishable features in the drug development process. Finally, several historical, structural and cultural factors influencing the shaping of medicines are revealed by the comparison between British and Japanese drug innovation. Addressing a number of practical implications for the promotion of the pharmaceutical industry, this book will be of enormous interest to students, researchers and academics specializing in science and technology, and the management of technology and innovation. Practitioners, managers, and policy planners within the pharmaceutical industry will also deem this book invaluable.
Опубликованы статьи, в которых рассматриваются проблемы развития отрасли туризма и сервиса, а также влияние их на смежные отрасли. Современные особенности развития туристской отрасли в условиях глобализации, роль туризма в устойчивом развитии сельской местности: Европейский опыт и возможности его применения в России, возможности инновационного развития российской экономики за счет туризма, современные тенденции в управлении туристскими объектами, информационные технологии в туризме и сервисе, социально-экономическая и экологическая ответственность туристской отрасли в свете обеспечения устойчивого развития. В сборнике представлены результаты научных исследований и практических разработок исследователей, аспирантов и студентов из вузов России, Украины, Сербии, Венгрии, Чехии, Литвы. The book of proceedings includes the papers concerned with the problems of tourist and service industry and their infl uence on the related sectors. Modern peculiarities of tourist industry in the conditions of globalization; role of tourism in sustainable rural development: European experience and its implementation in Russia; opportunities of innovation-driven growth of Russia’s economy by means of tourism; modern tendencies in management of tourist enterprises and attractions; information technologies in tourism and service; social and economic responsibility of tourism industry in relation with sustainable development. The journal includes the results of research and practical developments of scientists, post-graduate and undergraduate students of Russian, Ukranian, Serbian, Hungarian, Czech and Lithuanian higher professional institutions.
This title explores the issue of innovation engineering, a feature that is essential to the continuation of growth and development in the commercial world. Discussion is divided into three parts: Part I covers the historical basis of innovation, noting that diversity rests upon a duality between concepts in theory and applications put into practice, as well as discussing how innovation has resulted from the interaction of numerous factors, be they societal, human, managerial, organization or technological. Part II focuses on practical applications – the technologies, tools and methods employed in putting theoretical innovation into practice – while Part III looks at what factors underpin success, discussing the social and psychological aspects involved in successful innovation engineering. Consideration is also given to recent developments and systems which will assist in ensuring the continuation of this process in the future.
Intellectual Property (IP) and innovation are key management issues for today's enterprise. This timely book combines research on SMEs, IP and innovation. Drawing on original material from the ESRС's Programme on Intellectual Property, and showing a variety of approaches to the study of IP in small firms, this book reveals that IP and innovation management are interdisciplinary areas of research. These chapters provide new evidence on IP management in specific sectors such as software, engineering, textiles, biotechnology and electronic publishing. Some also address the strategic management of IP and examine IP management in the case of university spin-offs, while others focus on the role of patents in protection and innovation. The first major collected edition on IP and innovation management in SMEs, this book will be of interest to students, policy-makers and practitioners interested in IP and innovation.
From a leader in innovation best practices, 10 simple and practical steps your business must take to achieve profitable growth, through innovation In this timely guide, innovation expert and former CEO Robert Brands presents the best practices for today's «innovate or die» world, in the form of 10 simple and practical steps your business must take to achieve growth through innovation. Robert's Rules of Innovation™ simply, intelligently, and entertainingly creates order from the chaos imposed by today's misguided mandate for «addition by subtraction» profitability. Concisely, Robert's Rules of Innovation™ Distills Robert Brands' wealth of experience as a leader of international product development teams Explains why innovation is imperative Provides the practical steps needed to deliver innovation Draws upon the wisdom of global business leaders and is filled with real world examples, anecdotes, and practices Timely, accessible, and indispensable, Robert's Rules of Innovation™ is a road map for success through sustainable innovation with a clear message: innovation is the lifeblood of business and the secret to outperforming your competition. Direct and practical, Robert's Rules of Innovation™ is a must-read for managers at all levels.
«Made in Italy» is a worldwide label for fashion and luxury brands. It suggests top quality as well as a sense of distinction and it is closely linked to famous brand names as well as entrepreneurs like Giorgio Armani, Miuccia Prada, Gianni Versace. Nevertheless, behind the sparkling names, made in Italy hides a set of entrepreneurial forms that are at the heart of peculiar Italian savoir-faire for fashion and luxury goods and that were, indeed, at the heart of the economic development of the country. Design, production and distribution of fashion and luxury goods in Italy have solid foundations in a diffuse network of independent enterprises that ensured economic and cultural development and innovation. The free, yet coordinated, initiative of small entrepreneurs, firmly rooted in the traditional structure of the Italian society, constitute the economic and social fabric behind the success of some of the well known large groups of the high end of the fashion and luxury system. This fabric of diffuse entrepreneurship is also actually ensuring the necessary variety of initiatives and countermeasures to face the crisis of this sector and to invent new solutions against the de-manufacturing and the fierce concurrence of the developing countries.
This practical guide reveals the nine major “fatigue factors” that can block the path to innovation success, along with solutions to energize innovation. Original advances in innovation practice and new case studies are applied to guide inventors, entrepreneurs, companies, universities, and even policy makers in conquering innovation fatigue. Cost-effective solutions include guidance on intellectual assets, dealing with disruptive innovation, and driving innovation using the “Horn of Innovation” and “Circuit of Innovation” models. A surprising view of DaVinci as an engine of open innovation is presented. Throughout the book, a unique aspect is exploring the journey of innovators, including corporate employees and entrepreneurs, at the often-overlooked personal level using the metaphor of immigrants in a strange land to identify barriers and solutions.
With innovation fast becoming omnipresent and part of strategic matters, there is a growing need to understand how to jumpstart the innovation process. This book introduces the concept of «e-co-innovation,» which fosters the successful transition from idea to reality and ultimate value. It provides a global and system overview of the subject and presents various aspects of innovation from different angles and perspectives, leading to an understanding of all ecosystem components, their metamorphoses, cross-influences and possible impacts on the balanced development of people, businesses, regions and countries.
According to conventional wisdom, innovation is best left to the dynamic entrepreneurs of the private sector, and government should get out of the way. But what if all this was wrong? What if, from Silicon Valley to medical breakthroughs, the public sector has been the boldest and most valuable risk-taker of all?
This Task Force report reviews the evidence that the seeds of many adult diseases are sown in utero and in infancy. The report, written by experts in the field, summarises current knowledge in this area. It illustrates how early life nutrition can bring about changes in organ development and function, thus programming risk of disease in adult life. It also considers what might be done in early life to reduce the burden of future ill health. Nutrition and Development: Short- and Long-Term Consequences for Health includes chapters on the history of this topic area, normal growth and development, and current recommendations and practice in relation to nutrition and diet in early life. Chapters exploring the possible mechanisms and pathways of critical windows for development cover the effects of diet and nutrition in early life on organ and skeletal development, the role of sex hormones in programming disease susceptibility, the establishment of gastrointestinal microbiota, and the impact of early life nutrition on cognitive and neurological development. This new report: • describes how development occurs and explores how changes in the fetal and postnatal environment, such as over- or under-nutrition, can result in permanent alterations in function; • explains how diet and nutrition in early life can affect risk of adult disease, with specific chapters on allergic disease and asthma, bone health, cancer, cardiovascular disease, cognitive function, diabetes and obesity; • includes a summary of the key points, as well as recommendations in each chapter to help fill the gaps in our knowledge; • provides an overview of the main messages in a practical question and answer format suitable for lay readers. Nutrition and Development is an important information resource for those involved in research and teaching in the health sciences sector and is also of value to those involved in making decisions about health policy. It will be of interest to a broad range of health professionals, the food industry and those who write and broadcast about the effects of food on health.
Under the aegis of the African Energy Policy Research Network (AFREPREN) Capacity Building Theme Group, a regional study and four country studies (Zimbabwe, Mauritius, Ethiopia, and South Africa) addressed the capacity building question in the African power sector. This volume presents the findings of the studies. The studies analyze issues of manpower recruitment, training, and retention in national power utilities. They also highlight the challenges and implications of capacity building initiatives in a reforming electricity industry and propose innovative options for capacity building in the region's power sector.
The business leader's guide to encouraging continuous innovation in any organization Innovation governance is a hot topic in the business world. In a fast-paced business environment, the ability of corporate leaders to build purpose, direction, and focus for innovation is more important than ever. In this book, the authors provide a framework for encouraging and focusing innovation by explaining what innovation governance is, the various models for governance and their advantages and disadvantages, how to assess and improve governance practices, and behavioral tactics for maximizing the effectiveness of governance. It offers guidance for everyone from the boardroom through senior management, illustrating effective governance models with real case studies from a range of companies in the United States and Europe. Addresses an important yet underappreciated skill for CEOs, board members, and top management Features real-world examples and case studies from a variety of business from around the world Written by an author team with hands-on experience in the subjects of innovation management, organizational learning, innovation leadership, organizational behavior, and individual leadership and teamwork Innovation governance is a sadly neglected topic in many organizations. This book offers vital guidance and real-world experience for building innovation into any business from the top down.
New Product Development is one of the most important challenges facing organizations today. The Product Development and Management Association (PDMA) Handbook of New Product Development 3rd Edition provides an exceptional review of cutting edge topics for both new and experienced product development leaders. It offers a comprehensive and updated guide to the practices, processes and tools critical to achieving and sustaining new product/service development success in today’s world, delivering valuable information about the fundamentals as well as emerging practices such as venturing, virtual product development and the use of social media in NPD. As the premier global advocate for professionals and organizations working in the fields of new product/service development, PDMA has assembled in the Handbook unique content on the critical aspects of product development success including its 2012 Best Practices Research, Lessons Learned from its Outstanding Corporate Innovator Award Winners and keys to success from organizations with proven innovation track records. The 3rd Edition is an essential reference for anyone with responsibility for product development activities, from novices looking for fundamentals to experts seeking insights on emerging concepts, and is relevant for all functions and all product/service industries.
A consolidated and comprehensive reference on ligand-binding assays Ligand-binding assays (LBAs) stand as the cornerstone of support for definition of the pharmaco-kinetics and toxicokinetics of macromolecules, an area of burgeoning interest in the pharmaceutical industry. Yet, outside of the Crystal City Conference proceedings, little guidance has been available for LBA validation, particularly for assays used to support macromolecule drug development. Ligand-Binding Assays: Development, Validation, and Implementation in the Drug Development Arena answers that growing need, serving as a reference text discussing critical aspects of the development, validation, and implementation of ligand-binding assays in the drug development field. Ligand-Binding Assays covers essential topics related to ligand-binding assays, from pharmacokinetic studies, the development of LBAs, assay validation, statistical LBA aspects, and regulatory aspects, to software for LBAs and robotics and other emerging methodologies for LBAs. Highlights include: A general discussion of challenges and proven approaches in the development of ligand-binding assays More detailed examination of characteristics of these assays when applied to support of pharmacokinetic and toxicokinetic studies of compounds at different stages in the discovery or development timeline A concise, but detailed, discussion of validation of ligand-binding assays for macromolecules A practical approach to «fit-for-purpose» validation of assays for biomarkers, those molecules receiving increased attention as potentially demonstrating that the target chosen in discovery is being modulated by the candidate therapeutic, both in nonclinical and clinical studies Written by a team of world-recognized authorities in the field, Ligand-Binding Assays provides key information to a broad range of practitioners, both in the pharmaceutical and allied industries and in related contract research organizations and academic laboratories and, perhaps, even in the field of diagnostics and clinical chemistry.
The Nonprofit Leadership Transition and Development Guide In this dynamic resource, Tom Adams (an expert in succession planning who has worked with hundreds of organizations) shows how intentional leadership development and properly managed leadership transitions provide nonprofits with the rare opportunity to change direction, maintain momentum, and strengthen their capacity. This accessible guidebook is filled with illustrative stories, instructive lessons, best practices, and practical tools that can be used to ensure a successful nonprofit leadership transition. «It is terrific to have a book which so effectively addresses the unique challenges and opportunities of leadership in the nonprofit sector, replete with sound advice and concrete examples. Tom Adams brings a wealth of experience and savvy to the topic. Paid and volunteer leaders of nonprofits at all levels will benefit from reading it.»—Irv Katz, president and CEO, National Human Services Assembly «The guide is one of its kind in providing a realistic frame for the world of nonprofit leaders. It is long overdue in the sector as a real tool for leaders. Maybe even more important, it helps nonprofit boards of directors and philanthropic organizations to understand the connection between their investment in leadership and achieving organizational goals.» —Diane Bell McKoy, CEO, Associated Black Charities «Rich with instructive examples and advice, this book is grounded in the reality of nonprofits. It will be an extraordinarily useful guide to nonprofit organizations of all types and sizes.» —Ruth McCambridge, editor in chief, Nonprofit Quarterly «Make no mistake: attracting and retaining top talent should be priority number one for the nonprofit sector. Adams's book offers practical advice for how to embed this priority into the sector's DNA. All who care about nonprofit effectiveness would be well-served to give this book a close read.»—Kathleen P. Enright, president and CEO, Grantmakers for Effective Organizations